Anderson finally managed to become the first player who has taken John's serve at this year's Wimbledon, earning a break in game eight of the third set but his lead didn't last for long, getting broken in the following game when he served for the set. Returning Anderson's serve with a Djokovic-like brilliance, Isner had three break-points in the third game of the set, losing one of them to an undemanding backhand volley that he hit wide.
In the end, and to the surprise of no one, they did not come close to finishing after two hours and 54 minutes of play on Friday night.
"You feel like this is a draw for the two of us, but somebody has to win."
South African eighth seed Kevin Anderson has reached his first Wimbledon final, beating American ninth seed John Isner 7-6 (8/6) 6-7 (5/7) 6-7 (9/11) 6-4 26-24 in the longest semi-final in the tournament's history.
Maybe the most excruciating part of all is that Anderson now has to turn around and get ready for the championship on Sunday, while Isner has to face the harsh reality that this preposterous marathon match was all for naught.
At Wimbledon, there are no fifth-set tiebreaks, a rule with which Isner is extremely familiar, so one of the players was going to have to break the other's serve at least once in order to reach the final.
Nicole Melichar and Kveta Peschke upset sixth seeds Gabriela Dabrowski and Yifan Xu 6-3 4-6 7-5 in two hours and 16 minutes to reach the women's doubles final.
Djokovic was in the lead two-sets to one when play was halted.
They combined for 102 aces, 53 by Isner, 49 by Anderson.
The US Open is the only grand slam to use tiebreakers in the fifth set, with the Australian Open and French Open, like Wimbledon, both also playing advantage sets.
Anderson and Isner go way back, to their days when they played in college, Isner at Georgia, Anderson at IL.
"I think it's long overdue", Isner said.