In Logar Province, just to the south of Kabul, insurgents mounted an early morning attack on Wednesday against the First District Police Headquarters in the provincial seat of Pul-i-Alam, using a suicide vehicle bomb followed by three gunmen, according to Afghan police officials.
A local affiliate of the Islamic State (IS) extremist group has also launched a number of deadly attacks in recent months, including in Kabul.
More than 50 senior Taliban commanders were killed in an artillery strike in Afghanistan's southern province of Helmand, a us military spokesman said on Wednesday, as fighting continued across the country.
Another four police and eight civilians, including two children, were wounded in the attack early Wednesday, said Shah Poor Ahmadzai, spokesman for the provincial police chief.
Just after midday, a auto bomb exploded at the entrance to the ministry compound, said Hashmat Stanekzai, spokesman for Kabul police.
"We think the meeting was to plan next steps", said Lt. Col. Martin O'Donnell, spokesman for USA forces in Afghanistan.
Both the Taliban and IS frequently target Afghanistan's Western-backed government and its security forces.
Elsewhere in Afghanistan, the Taliban attacked a district headquarters in the northern Takhar province, killing five security forces, according to provincial police spokesman Khalil Asir.
Three attackers, wearing military uniforms, detonated explosives while the others were shot by government troops, officials said.
The assault marks the latest clash between Afghanistan's security forces and insurgents who have carried out a host of attacks in recent weeks, and again highlights a worsening security situation inside the country.
The Islamic State militant group claimed responsibility for the attack, according to RFE.
And in northern Samangan province, a provincial hospital director was killed when a sticky bomb attached to his auto detonated on Tuesday in the provincial capital, Aybak, according to Sediq Azizi, the provincial spokesman.
The attack began around noon when a group of 10 militants tried to storm the ministry compound in Kabul, Danish said.
The Taliban claimed the attack.
"But our police said that at least two civilians were either killed or injured in today's attack", he said. "We were told to stay inside our offices as the compound was attacked", said one ministry employee.