The contest for the Florida Senate seat could decide which party controls the Senate.
Scott made his announcement Monday on facebook. Both political parties share some of the blame. It also offers a test of whether a tight alliance with Trump provides more help or harm in the current political environment. Scott will challenge three-term Democratic incumbent, Bill Nelson.
During his campaign speech, Scott cited the turnaround in Florida's economy during his time in office.
But Nelson, 75, seemed unfazed by Scott's candidacy.
Democrats are defending 10 seats in states Trump won in 2016, including Florida. Let's Get to Work!
Mr. Nelson has said that Mr. Scott hadn't gone far enough, with the increase in the purchase age representing only the "bare minimum". "But I will not accept the idea that we can't change Washington". Thats one reason Scott wants to make term limits an issue in this race, besides the obvious populist appeal. A Quinnipiac University poll of Florida voters in late February found that Trump had only a 42 percent approval rating. During a tour of storm damage during Hurricane Irma in September, the president told reporters: "I hope this man right here, Rick Scott, runs for the Senate".
"I won't fit in in Washington either", Scott said. "I don't consider myself any type of anything. I'm going to run to win", Scott said. "I'm sick of it", Scott said. "I know he's asked me to get into the race". "Floridians won't forget the damage Rick Scott's self-serving politics have done these last 7 years, no matter how he tries to change his spots and obscure his record". "I believe in jobs".
The announcement did not come as a surprise, as no other major Republican candidate has expressed an interest in running against incumbent Democrat Bill Nelson.
Over the last few years the governor has relentlessly traveled the state to promote businesses that are adding jobs. "I mean the list just goes on and on and on".
That line is nearly an understatement for Scott: The "jobs" message is the raison d'être for his political identity, born in 2010 when faith in the state and national economy were low and unemployment numbers were high.
Democrats have been gearing up for the campaign running video spots critical of Scott's terms as governor and his actions in the business world.
Democrats have been anticipating Scott's move and have ramped up criticism, noting that he was forced out as chief executive of Columbia/HCA amid a federal fraud investigation.
The Governor's office says Bustamante had also served as Press Secretary for Lt. Governor Carlos Lopez-Cantera during the reelection campaign and assisted with Hispanic media outreach.
Trump won Florida in the presidential election two years ago, but President Barack Obama carried the state in the two previous elections. The announcement came shortly after Interior Secretary Ryan Zinke had moved to allow new drilling in almost all United States coastal waters.