Pep Guardiola has never worked with Neymar with the forward joining Barcelona from Santos in 2013, a year after Guardiola had departed.
Neymar became the world's most expensive footballer when he joined Paris Saint-Germain from Barca in a deal worth €222million in August, but he is reportedly unhappy with life in the French capital.
Real Madrid are understood to be interested in singing Neymar from PSG.
Neymar has amassed 19 goals and 13 assists in just 20 league games for the Parisian club, and yet the season as a whole will be deemed a failure given PSG's inability to reach the latter stages of Europe's premier club competition.
"To be honest, Neymar's future is not something I'm thinking about", Iniesta told Spanish radio show El Larguero, as quoted on FourFourTwo.
"He's a professional and it's not that far fetched, but I think it'll be hard for him to leave PSG because they spent a lot of money on signing him". And given Real Madrid's form this season, many expected their opposition PSG to be the team going through, but Zidane and co, proved everyone wrong.
Real head coach Zinedine Zidane refused to be drawn on speculation linking the Bernabeu club with a summer move for Neymar last week.
Widely considered the best out and out winger in the world at the time of his switch, Bale has failed to live up to expectation on a personal note, and has struggled greatly with injury.
Meanwhile, Iniesta also spoke about his own future with his boyhood club as his current contract holds a stipulation that could see him leave at the end of the season, with China being a possibility.
Iniesta: I Will Only Stay At Barca If. It will not be a matter of love, it will be about me feeling what I think I am able to contribute.