E-cigarettes and DNA damage

Vaping may raise cancer and heart disease risk, study suggests

E-cigarettes could raise risk of cancer and heart disease, warn scientists

The report found vaping was likely to be less harmful than conventional cigarettes. The FDA panel concluded there wasn't enough proof to state that the device was a safer way to ingest tobacco and nicotine. This list of extra chemicals includes allergens, irritants, and cancer-causing carcinogens.

Vaping may raise the risk of certain cancers and heart disease, according to a team of scientists who studied the effects of e-cigarette smoke on healthy mice and human cells. The chemists wrote that the damage caused by vaping increased as a person took more puffs of an e-cigarette. Any "safety" may come from the level of exposure.

Post-ECS, the mice showed increased evidence of adducts, modifications to DNA that form when a chunk of DNA binds to a chemical, altering the structure of the DNA and increasing the risk for mutation. Their organs were likewise less able to fix DNA.

The results showed that vapor damages DNA and reduces DNA fix activity in the lung, heart, and bladder of mice.

Cells in the mice mutated and became cancerous at a much higher rate than in a control group of animals that breathed filtered air.

The more than 600-page report examined the health consequences of e-cigarettes with regards to the population as a whole. The wide variety of flavors, which has produced exotic taste combinations such as lychee and lemon sorbet, are the biggest draw for young smokers. The amount of nicotine in the vapour was 10 milligrams per millilitre, making it as concentrated as the e-cigarette smoke that humans inhale.

Give up Vaping to Avoid Cancer?

"Based on these results I can not conclude that E-cig smoke is safer than tobacco smoke in terms of cancer susceptibility of smokers".

E-cigarette smoke delivers nicotine through aerosols without burning tobacco. "But compared to smoking, the evidence so far shows they are less harmful", it said in statement. Nicotine inhaled from e-cigarettes could be converted into chemicals that damage DNA in the heart, lungs and bladder, according to the study.

All in all, a rather unclear picture emerges.

Vaping could increase the risk of youth smoking but would be less risky to health than smoking cigarettes, according to a report from the Academies of Science and Medicine published Tuesday, presented as the most extensive on the subject so far. Whether or not Tang's research into nicotine by-products changes that conclusion remains to be seen.

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