Nursing home officials at the facility set up portable coolers and fans in response, and reached out to Florida Power & Light and called the governor's cellphone in the next two days.
Franco's husband, 93-year-old Miguel Franco, also died after the tragedy.
The state closed the nursing home down after eight residents died from sweltering heat on September 13 due to Irma knocking out the center's air-conditioning system.
Despite multiple calls between the nursing home and state authorities, the nursing home did not report that its patients were in danger or that they needed to be evacuated, according to a report last month by Florida Gov. Rick Scott's office.
Cecilia Franco, 90, died in hospice at 3:45 a.m. Monday, according to family attorney Albert Levin.
Franco lived only 26 days after her husband of 61 years, Miguel Antonio Franco, died along with seven other residents in the first run of deaths.
More than 100 patients were evacuated from the home on September 13 after three patients were found dead.
Cecilia Franco was described by family lawyers as being in a serious condition when she was evacuated to St. Catherine's Rehab Hospital in Hialeah.
"The respondent's (nursing home's) deficient conduct is widespread and places all future residents at immediate threat to their health, safety and welfare", the order said.
Laid off were certified nursing assistants, licensed practical nurses, occupational or physical therapists, registered nurses, doctors, environmental or laundry workers, administrative assistants "and others who worked in activities, dietary aid, engineering and supplies", the report said.